★★★★★
Third refill and counting
The swap takes ten seconds. Ordering the three-month supply means I stop thinking about it.
NAD+ Pen Refill Kit — 1000mg
£285.00
Sale price
£285.00
Regular price
£355.00
For people who already own the pen. Two sealed cartridges — 1000mg of pure NAD+ between them — plus every consumable the month asks for. Same ritual, no repeat hardware.
This is the part of the system that repeats. The pen is bought once; the NAD+ is what you actually use. Set the supply length that matches how you dose and keep the rhythm going without thinking about it.
What's in the box
- 2 × 500mg / 3ml NAD+ cartridges (1000mg total, 20 doses)
- 20 × sterile, individually wrapped micro-needles
- 20 × antibacterial wipes
- 1 × sharps bin for safe disposal
- 1 × quick-reference dosing card
Doesn't include the auto-injector pen or the travel case — if you're starting from scratch, the Injection Pen Kit is the one you want.
How to use it
Each cartridge holds ten 50mg doses (0.3ml). The usual rhythm is one dose daily for the first three days, then every other day — roughly five weeks across the two cartridges. Let the cartridge come up from fridge temperature for 20–30 minutes before you seat it, dose at 45° into the stomach, hip or outer thigh, and rotate the site each time.
Good to know
- Storage: cartridges in the fridge; everything else at room temperature.
- Shelf life: 12 months unopened.
- Colour: clear to faintly yellow is normal — that's the NAD+, not a fault.
- Compatibility: fits every NAD+ Injection Pen we sell. If your pen came from elsewhere, check the cartridge seat before ordering.
Is it for me?
Adults 18+. Not suitable during pregnancy or breastfeeding, or if you have a current or previous cancer diagnosis, an organ transplant, immunosuppression, a heart-rhythm condition such as atrial fibrillation, or significant liver or kidney impairment. If you take prescribed medication or you're unsure, speak to your doctor before starting.
Feel better, longer.
Food supplement for adults. These statements have not been evaluated by a regulatory body and are not intended to diagnose, treat, cure or prevent any disease.
Fits every NAD+ pen we sell
Standard 3ml cartridge seat
1000mg across 2 cartridges
20 doses — about five weeks
Consumables included
20 needles, 20 wipes, sharps bin
1, 2 or 3 month supply
Buy the rhythm that matches yours
01 — Benefits
Why consistency is the whole point
NAD+ isn't a one-off. Your cells spend it continuously, which means the benefit comes from the rhythm, not the first dose. This is the resupply that keeps the rhythm from breaking.
01Cellular Energy
+
NAD+ fuels the mitochondria — the engines inside every one of your cells. Raising NAD+ lifts ATP production for sustained energy that doesn't depend on stimulants.
The engine, not the stimulant
02Mental Clarity & Focus
+
NAD+ is a cofactor in the synthesis of neurotransmitters tied to attention and mood. People report cleaner focus and less afternoon fog.
03Faster Recovery
+
Effort depletes NAD+ stores. Replenishing them shortens the recovery window after training, travel and high-load weeks.
04Longevity & DNA Repair
+
NAD+ activates sirtuins — proteins associated with cellular longevity, DNA repair and metabolic regulation.
Backed by sirtuin research
05Deeper Sleep
+
NAD+ helps regulate the circadian rhythm via the SIRT1 pathway, supporting cleaner sleep and mornings that don't feel borrowed.
06Skin & Visible Ageing
+
Visible markers of ageing track cellular energy decline. Restoring NAD+ supports the machinery that keeps skin functioning the way it did a decade ago.
02 — How to use
How to use your NAD+ Pen Refill Kit
You already know the routine. This is just the swap, plus a reminder of the protocol.
-
01
Swap when the pen runs dry
When a cartridge is empty, unscrew the pen, remove the spent cartridge and drop in a fresh one. Both cartridges in this kit are identical.
-
02
Warm it before you dose
Twenty to thirty minutes out of the fridge. It makes the injection noticeably more comfortable.
-
03
Fresh needle, every time
Attach a new sterile micro-needle for each dose. Twenty are included — one per dose in this kit.
-
04
Prime, then inject
Dial 0.3ml, prime until a bead appears, then inject at 45° into a fatty area and rotate the site.
-
05
Dispose and restock
Used needles into the sharps bin. When you're on your last cartridge, that's the moment to reorder.
Protocol: one dose daily for the first three days of a cycle, then every other day. Ten 50mg doses (0.3ml) per cartridge, twenty per kit — roughly five weeks. Cartridges live in the fridge.
03 — FAQs
Frequently asked questions
The questions customers ask most before starting. Anything missing? Talk to us.
Will this fit my pen? +
Yes, if your pen came from us — the cartridges fit every NAD+ Injection Pen we sell. If your pen came from somewhere else, check that it takes a standard 3ml cartridge before ordering, or message us and we'll help you check.
What's not included? +
The auto-injector pen and the travel case. This is a resupply — you keep the hardware from your original kit. If you're starting from scratch, the NAD+ Injection Pen Kit is the one you want.
What do the 1, 2 and 3 month options mean? +
They're multiples of the same kit, priced so the longer you commit the less you pay per dose. One month is 1000mg and 20 doses. Choose whichever matches how often you actually dose — there's no penalty for going back to a shorter supply.
Should I take a break between refills? +
Most people don't. Some prefer to run a cycle, take a week off, then start again. Because NAD+ is spent continuously rather than stored, consistency generally beats intensity — the day-on-day-off rhythm is the one most people settle into.
How do I store the spare cartridge? +
In the fridge, sealed, until you need it. Unopened cartridges keep for 12 months, so buying a longer supply doesn't put you at risk of waste.
I only need a top-up, not a full refill. +
Then the single 500mg cartridge is the better buy — ten doses, needles and wipes included, about two and a half weeks.
Who shouldn't use it? +
Adults 18+ only. Not suitable during pregnancy or breastfeeding, or if you have a current or previous cancer diagnosis, an organ transplant, immunosuppression, a heart-rhythm condition such as atrial fibrillation, or significant liver or kidney impairment. This product is not intended to diagnose, treat, cure or prevent any disease. If you take prescribed medication or you're unsure, speak to your doctor before starting.
Still have questions?
Talk to a human
04 — Reviews
What our customers say
4.9 / 5
based on 74 reviews
★★★★★
Cheaper than starting over
Glad I didn't have to rebuy the pen. The refill is the sensible way to keep going.
★★★★★
Arrives cold and sealed
Packaging has been perfect every time, even in July.
★★★★★
Wish I could set and forget
Great product. I'd take a subscription the moment they offer one.
Reviews shown are illustrative placeholders and will be replaced with verified customer feedback.